Semaglutide Txhaj (CAS 910463-}68-2) yog tib neeg glucagon-zoo li peptide-1 (GLP-1) analog uas tsim los ntawm recombinant DNA technology siv Saccharomyces cerevisiae. Raws li ib tug tom ntej no - tiam ntev-acting GLP-1 receptor agonist polypeptide, nws nta ib zaug ib lub lim tiam koob tshuaj, glucose-dependent hypoglycemic mechanism, thiab cov txiaj ntsig tseem ceeb ntawm cov hlab plawv, ua rau nws yog cov tshuaj blockbuster rau hom 2 mob ntshav qab zib thiab kev tswj qhov hnyav mus ntev.
Yog tias koj tab tom nrhiav rau Tuam Tshoj Semaglutide Txhaj Tshuaj, peb GMP-cov chaw muaj ntawv pov thawj muaj kev ntseeg siab. Koj tuaj yeem yuav Semaglutide Txhaj Tshuaj ncaj qha los ntawm peb lub Hoobkas nrog cov ntaub ntawv zoo. Ntau tus neeg siv khoom kuj nrhiav kev txhaj tshuaj semaglutide online - peb muab kev nyab xeeb thoob ntiaj teb kev thauj khoom thiab kev tswj hwm kev txhawb nqa.
Technical Specifications
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Khoom npe |
Semaglutide Txhaj |
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Synonyms |
ozempic txhaj tshuaj poob phaus, semaglutide ntsiav tshuaj |
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Yam ntxwv |
Xyaum tsis muaj xim lossis ze li tsis muaj xim, ntshiab isotonic kua |
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CAS Nr |
910463-68-2 |
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Assay |
Ntau dua lossis sib npaug li 98.5% (HPLC, Raws li COA) |
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Formula |
C187H291N45O59 |
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Pob |
Pob txheej txheem |
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Cia |
Khaws ntawm 2-8 degree |
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Qauv |
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Raws li kev ntseeg siab Tuam Tshoj Semaglutide Txhaj Tshuaj, peb khaws Semaglutide Txhaj hauv Tshuag kom xa khoom sai. Bulk Semaglutide Injection xaj yog txais tos rau ob qho tib si API thiab cov ntawv ua tiav.
Khoom nta
Ntev - ua yeeb yam, ib zaug - noj txhua lub lim tiam
Los ntawm kev hloov pauv molecular (qhia txog Aib ntawm txoj haujlwm 8 los tiv thaiv DPP-4 degradation, thiab txuas ntawm C18 fatty diacid saw ntawm Lys26 rau albumin khi), ib nrab - lub neej txuas ntxiv mus rau ~ 7 hnub, ua rau kev tswj hwm ib zaug ib lub lim tiam nrog cov ntshav plasma tsis tu ncua thiab ua raws li tus neeg mob siab.
Glucose-dependent hypoglycemia nrog kev pheej hmoo ntawm hypoglycemia tsawg heev
Stimulates insulin secretion thiab inhibits glucagon tso tawm tsuas yog thaum cov ntshav qabzib nce siab, kom tsis txhob muaj ntshav qab zib. Hauv Suav cov neeg mob T2DM, HbA₁c txo mus txog 1.8% thiab lub hom phiaj tus nqi (<7.0%) up to 86.1%.
Kev poob phaus tseem ceeb thiab ntau yam txiaj ntsig metabolic:Suppresses qab los noj mov, tsub kom satiety, ncua lub plab khoob. Hauv kev sim STEP UP, 7.2 mg ib zaug -ib lub lim tiam ua tiav qhov hnyav poob ntawm 20.7%, nrog ~ 1/3 ntawm cov neeg koom ua tiav ntau dua lossis sib npaug li 25% poob phaus. Kuj tseem txhim kho systolic / diastolic BP, triglycerides, thiab CRP.
Clear cardiovascular tiv thaiv:SUSTAIN 6 tau pom tias 26% txo qis hauv MACE thiab 39% txo qhov tsis yog- mob stroke. SELECT kev sim txuas ntxiv tau txais txiaj ntsig rau cov tsis yog- cov neeg mob ntshav qab zib rog rog nrog CVD (txo 20% MACE).
Stable physicochemical zog:Ntshiab isotonic kua, pH 7.4, dej solubility zoo heev. Muaj nyob rau hauv ob qho tib si txhaj tshuaj thiab qhov ncauj ntsiav tshuaj, txhawb nqa txoj kev sib txawv.
Full -Cycle Quality Control & Consistent Quality
- Xaus -mus rau- kawg traceability: Microbial fermentation siv genetically engineered Saccharomyces cerevisiae, ua raws li extraction, purification, thiab tshuaj hloov kho. HPLC, MS, NMR yog siv rau qhov hnyav molecular, purity, thiab cov qauv kev pom zoo. Txhua pawg muaj ntau tus lej tshwj xeeb nrog cov ntaub ntawv tsim tawm tiag - lub sijhawm.
- Strict standards compliance: RP-HPLC purity >99.0%, kev tswj nruj ntawm cov protein ntau molecular, cov kab mob endotoxins, residual DNA, thiab host cell proteins. Ua raws li CP, USP, EP, thiab ICH Q7. Qee tus neeg xa khoom tau ua tiav FDA DMF cov ntaub ntawv.
- Kev txhim kho kom tsis tu ncua: kev siv tau cov txheej txheem ib xyoos ib zaug, kev sib txawv ntawm kev tswj hwm, kev hloov pauv, kev tshawb fawb ruaj khov, thiab kev tshuaj xyuas txhua xyoo kom paub meej cov khoom sib xws -rau -batch sib xws.
Thaum koj yuav Semaglutide Txhaj Tshuaj rau kev kho mob lossis kev lag luam siv, peb cov khoom yog Semaglutide Txhaj hauv Suav teb nrog kev lees paub thoob ntiaj teb.
Daim ntawv thov Scenario
Semaglutide Txhaj yog siv dav hauv cov chaw kho mob thiab R & D:
Hom 2 mob ntshav qab zib mellitus glycemic tswj
Rau cov neeg laus uas muaj T2DM tswj tsis txaus ntawm kev noj haus / kev tawm dag zog ntxiv rau metformin thiab / lossis sulfonylureas. Ib zaug - txhaj tshuaj subcutaneous txhua lub lim tiam pib ntawm 0.25 mg, titrated rau 0.5 mg lossis 1 mg. SUSTAIN series kev sim (nrog rau 605 tus neeg mob Suav) tau lees paub qhov ua tau zoo thiab kev nyab xeeb.
Txo kev pheej hmoo mob plawv
Qhia rau cov neeg laus T2DM nrog tsim CVD kom txo tau MACE (mob plawv tuag, tsis yog-mob MI, lossis tsis- mob stroke). SELECT kev sim txuas ntxiv tau txais txiaj ntsig rau cov uas tsis yog- cov neeg mob ntshav qab zib rog / rog rog nrog CVD. Kev sim STRIDE tau pom pob taws - brachial Performance index txhim kho ntawm 5% hauv PAD cov neeg mob tom qab 52 lub lis piam.
Ntev - tswj qhov hnyav
Qhov hnyav -poob version (Wegovy®) yog thawj zaug thiab tsuas yog ib zaug -GLP txhua lub limtiam-1 receptor agonist rau kev tswj qhov hnyav hnyav. 2.4 mg ib zaug-ib lub lis piam rau 68 lub lis piam ua tiav ~ 14.9% txhais tau tias poob phaus (50.5% ua tiav Zoo dua los yog sib npaug li 2% 1.5%). Thaum Lub Peb Hlis 2026, FDA pom zoo Wegovy® HD (7.2 mg ib zaug ib lim piam) nrog 20.7% txhais tau tias poob phaus.
MASH tshuaj txhim kho
2025 post-hoc tsom xam pom tias semaglutide 2.4 mg tuaj yeem txo qhov mob siab thiab txhim kho fibrosis hauv cov neeg mob MASH, ywj siab ntawm qib poob.
Generic thiab innovative tshuaj txoj kev loj hlob
Cov txheej txheem meej meej thiab cov ntaub ntawv kev nyab xeeb uas paub tab txhawb kev txhim kho ntawm qhov ntev - ua yeeb yam, txhawb nqa - tso tawm, thiab kev sib xyaw ua ke. Kev ua raws li tag nrho EP / USP pab txo cov generic R&D cycles thiab txo cov kev pheej hmoo ua ntaub ntawv.
Ntim thiab thauj
Professional ntim:API khaws cia tsawg dua lossis sib npaug li -15℃(ruaj khov rau 18 lub hlis); Tom qab hloov kho, ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv aseptic mob. Kev txhaj tshuaj tiav khaws cia ntawm 2-8 degree, tiv thaiv los ntawm lub teeb, tsis txhob khov. Customized ntim muaj (milligram kaw vials rau R&D, kilogram kaw nruas rau kev siv). Tag nrho cov pob khoom tau sau nrog cov ntaub ntawv khoom, batch naj npawb, hnub tas sij hawm, thiab kev cia khoom.
Ua raws li txoj cai txias chain logistics:Qhov kub thiab txias- saib xyuas cov hlua txias nrog kev taug qab tag nrho. Ua kom tiav cov kev tsim nyog xa tawm, cov ntaub ntawv pov thawj kev lis kev cai, thiab kev xa khoom xa tuaj ua kom sai, raws li kev xa khoom thoob ntiaj teb.
Peb nkag siab tus nqi txhaj tshuaj semaglutide yog qhov kev txhawj xeeb tseem ceeb rau cov neeg siv khoom. Raws li lub Hoobkas ncaj qha, peb muab cov nqi sib tw. Koj tuaj yeem yuav cov ntsiav tshuaj semaglutide yuav hauv online rau kev xav tau ntawm qhov ncauj. Ntau tus neeg siv khoom nrhiav kev txhaj tshuaj semaglutide online - peb muab kev nyab xeeb, taug qab kev xa khoom nrog cov ntaub ntawv tswj hwm.
Peb Qhov Zoo
Siab -kev ruaj ntseg zoo
From GMP-certified facility, RP-HPLC purity >99.0%, nruj impurity tswj. Txhua batch suav nrog ua tiav daim ntawv tshaj tawm (COA, HPLC, MS, NMR, siab molecular yuag proteins, endotoxins, residual DNA, cov ntaub ntawv ruaj khov). Qee tus neeg xa khoom tau ua tiav FDA DMF cov ntaub ntawv.
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Kev xa khoom yooj yim & kev pabcuam thoob ntiaj teb
milligram rau kilogram nplai, muaj zog Tshuag muaj. Peb muab Customized Semaglutide Txhaj Tshuaj (purity, particle loj, ntim). Peb 7 × 12 teev kev txhawb nqa ntau hom lus ua kom cov lus teb ceev ceev. Bulk Semaglutide Txhaj yog muaj rau loj - teev ntau lawm.
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R & D txhawb nqa & qauv dawb
Peb muab Semaglutide Txhaj Tshuaj Dawb Qauv rau kev tshuaj ntsuam xyuas, txoj kev txhim kho, thiab kev sim ua ntej-cov qauv zoo tib yam rau cov khoom lag luam. Kuj tseem muaj: cov ntsiav tshuaj semaglutide yuav online rau qhov ncauj formulation R & D.
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Cov ntaub ntawv pov thawj tag nrho
Ua tiav cov ntaub ntawv suav nrog COA, HPLC / MS / NMR spectra, siab molecular yuag protein tsom, cov tshuaj muaj feem xyuam, cov kab mob endotoxins, microbial txwv, residual DNA / proteins, cov ntaub ntawv ruaj khov, thiab cov txheej txheem cov ntsiab lus-txhawb kev sau npe thoob ntiaj teb hauv Suav teb, US, EU, Nyiv, Southeast Asia, thiab lwm yam.
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Raws li ib tug ua Tuam Tshoj Semaglutide Txhaj Hoobkas, peb kuj muab lwm yam GLP-1 analogs. Semaglutide Txhaj Tshuaj ua nyob rau hauv Suav teb los ntawm peb cov nroj tsuag tau ntseeg los ntawm cov tuam txhab tshuaj thoob ntiaj teb.
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FAQ
Yog xav paub ntxiv txog Kev Txhaj Tshuaj Semaglutide, kev txhaj tshuaj semaglutide online, lossis thov kom Semaglutide Txhaj Tshuaj Dawb, thov hu rau peb. Peb yog koj qhov txhim khu kev qha Tuam Tshoj Semaglutide Txhaj tshuaj muab cov nqi sib tw semaglutide txhaj tshuaj thiab cov kev pabcuam tshaj lij.
Cim npe nrov: Kev txhaj tshuaj Semaglutide, Hom 2 Ntshav Qab Zib
