HK Neopharm Limited yog ib qho ntawm feem txhim khu kev qha manufacturers thiab lwm tus neeg ntawm dexmedetomidine hydrochloride txhaj nyob rau hauv Suav teb, featured los ntawm cov khoom zoo thiab cov nqi zoo. Thov so assured mus yuav cov tshuaj dexmedetomidine hydrochloride hauv Tshuag ntawm no thiab tau txais cov lus hais los ntawm peb lub hoobkas. Customized xaj yog txais tos.
Dexmedetomidine HCl Txhaj yog ib qho kev xaiv zoo heev ₂-adrenergic receptor agonist rau cov tshuaj sedation. Raws li ib tug tseem ceeb sedative nyob rau hauv perioperative thiab intensive kev saib xyuas, nws nta tshwj xeeb kev kho mob zoo xws li sedation, analgesia, anxiolysis, ruaj khov hemodynamics, thiab tsis muaj teeb meem ua pa nyuaj. Nws yog qhov nyiam sedative pom zoo los ntawm kev siv tshuaj loog thiab ICU cov lus qhia thoob ntiaj teb.
Technical Specifications
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Khoom npe |
Dexmedetomidine hcl txhaj |
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Synonyms |
Dexmedetomidine HCl Txhaj |
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Yam ntxwv |
Colorless ntshiab kua |
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CAS Nr |
145108-58-3 |
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Assay |
Ntau dua los yog sib npaug rau 99.0% (HPLC, Raws li COA) |
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Formula |
C₁₃H₁₆N₂·HCl |
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Pob |
Pob txheej txheem |
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Cia |
Khaws ntawm 2-8 degree |
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Qauv |
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Ua los ntawm siab -purity dexmedetomidine hydrochloride raw cov ntaub ntawv siv sterile npaj technology, Dexmedetomidine 1ml thiab Dexmedetomidine 2ml feature nruj impurity tswj, zoo heev stability, thiab zoo batch - mus rau -batch sib xws. Lawv ua tau raws li tag nrho -scenario kev kho mob xav tau ntawm kev siv tshuaj loog dav dav adjuvant sedation, ICU mechanical ventilation sedation, preoperative anxiolysis, thiab procedural sedation, muab kev nyab xeeb, tswj tau, thiab arousable siab - zoo sedation daws rau tshuaj loog. thiab kev saib xyuas tseem ceeb
Khoom nta
Dexmedetomidine HCl Txhaj tau ua tiav qhov kev xav tau, yooj yim sedation xeev nrog kev nco qab meej los ntawm kev xaiv stimulating ₂ receptors nyob rau hauv locus coeruleus, mimicking ntuj pw tsaug zog. Qhov no distinguishes nws los ntawm cov pa sedatives thiab txhim kho kev nyab xeeb thiab yooj.
Kev nyab xeeb ua pa siab: Tsis muaj kev nyuaj siab ua pa tseem ceeb ntawm kev siv tshuaj sedative zoo, txo qhov kev pheej hmoo ntawm kev ua pa hauv ICUs thiab cov chaw perioperative.
Kev ruaj khov hemodynamics: inhibits kev ua siab ntev ntev, ua kom lub plawv dhia thiab ntshav siab, txo qis myocardial oxygen noj thiab kev ntxhov siab raug mob, thiab txhim kho kev nyab xeeb perioperative.
Synergistic analgesic effect: Txhim kho qhov ua tau zoo ntawm opioids thiab tshuaj loog, txo lawv cov tshuaj, thiab txo qis cov kev phiv xws li xeev siab, ntuav, thiab rov qab qeeb.
Anxiolysis thiab tiv thaiv- tshee: Relieves preoperative ntxhov siab vim thiab intraoperative kev nyuaj siab, zoo tiv thaiv thiab kho tom qab- tshuaj loog tshee, thiab txhim kho cov neeg mob kev nplij siab.
Tsim nyob rau hauv nruj raws li thoob ntiaj teb cov qauv GMP nyob rau hauv ib tug B + A qib cleanroom ib puag ncig, Dexmedetomidine 0.1mg thiab Dexmedetomidine 0.2mg undergo lub davhlau ya nyob twg sterilizing pom, aseptic filling, 100% kev soj ntsuam pom, thiab tshuaj ntsuam pyrogen kom paub meej sterility {4} zoo, {5} pyrogen, Cov ntsuas tseem ceeb suav nrog cov tshuaj muaj feem xyuam, enantiomers, pH tus nqi, thiab osmotic siab raws li cov tshuaj pharmacopoeia thiab ICH cov cai. Cov khoom ruaj khov thiab cov ntaub ntawv taug qab tau muab kev txhawb nqa txhim khu kev qha rau kev tsim kho, kev ntsuas kev sib xws, thiab daim ntawv thov sau npe.
Full -Cycle Quality Control & Consistent Quality
Qhov zoo yog qhov tseem ceeb ntawm kev sib tw ntawm Dexmedetomidine HCl Txhaj. Peb tau tsim kom muaj tag nrho - txheej txheem tswj kev ua tau zoo los ntawm cov khoom siv raw khoom nkag mus rau cov khoom tiav tso tawm, txhawb kev kho tshuaj thiab tshuaj R&D thiab sau npe nrog kev ruaj khov thiab txhim khu kev qha.
Cov khoom siv raw thiab kev npaj tswj tsuas yog siab -purity dexmedetomidine hydrochloride raw cov ntaub ntawv ua raws li cov qauv tshuaj pharmacopoeia yog siv thiab kuaj tag nrho ua ntej siv. Kev npaj yog tsim los ntawm cov dej tsis huv rau kev txhaj tshuaj, nrog kev tswj nruj ntawm pH (4.0-6.0) thiab osmotic siab. Lub formulation stability yog optimized los tiv thaiv crystallization thiab degradation, tswj impurities thiab isomers los ntawm qhov chaw.
Cov txheej txheem sterile thiab purification assuranceCov tag nrho cov khoom yog nqa tawm nyob rau hauv kaw aseptic tej yam kev mob, nrog 0.22μm sterilizing pom, nitrogen-purged filling, thiab terminal sterilization kom zoo tswj cov kab mob, endotoxins, thiab pom hais. Cov khoom tiav tiav tau dhau los ua ntau- theem pom thiab tshuaj xyuas qhov muag kom paub meej, cov yam ntxwv ruaj khov, thiab ua raws li cov cai nruj nruj rau kev txhaj tshuaj.
Kev ntsuam xyuas thiab tso tawm kev tswj xyuas Txhua pawg ntawm Dexmedetomidine 1ml thiab Dexmedetomidine 2ml yog muab nrog daim ntawv qhia ua tiav COA npog cov lus piav qhia, kev txheeb xyuas, pH, muaj feem xyuam rau cov tshuaj, isomers, tshuaj ntsuam xyuas, tsis muaj menyuam, cov kab mob endotoxins, cov khoom pom, thiab lwm yam khoom tiav. Cov ntaub ntawv ntsuam xyuas tuaj yeem ua tiav nrog cov khoom zoo heev - mus rau -batch sib xws, ua tau raws li cov qauv zoo rau kev siv tshuaj kho mob, R&D pilot batches, thiab daim ntawv thov sau npe.
Cov khoom lag luam ruaj khov thiab sib xws Ib qho kev ua tiav kev ruaj ntseg suav nrog kev ntsuas kev ntxhov siab, kev sim nrawm, thiab kev soj ntsuam ntev ntev yog tsim los xyuas qhov ruaj khov nyob rau hauv lub teeb- pov thawj, txias, thiab kaw cov xwm txheej. Degradation thiab impurity loj hlob yog tswj tau zoo, xyuas kom tsis muaj kev hloov pauv tseem ceeb hauv cov tsos, tshuaj ntsuam xyuas, thiab cov khoom muaj feem xyuam thoob plaws lub neej txee, yog li lav kev nyab xeeb thiab siv tau zoo.
Daim ntawv thov Scenario
Dexmedetomidine HCl Txhaj yog tsuas yog siv rau sedation nyob rau hauv perioperative thiab intensive kev kho mob chaw, npog cov chaw kho mob thiab R & D scenarios nyob rau hauv ntau lub tuam tsev:
Tshuaj loog thiab phais sedation:
Sedation rau endotracheal intubation thiab mechanical ventilation nyob rau hauv cov tshuaj loog, pab induction thiab txij nkawm ntawm tshuaj loog, stabilizing ncig, thiab txo cov tshuaj loog.
ICU kev kho mob tseem ceeb sedation:
Sedation rau intubated thiab mechanically ventilated cov neeg mob nyob rau hauv intensive care units, nrog tas li infusion mus txog 24 teev, muaj kev ruaj ntseg kam rau ua, yooj yim arousal, thiab yooj yim rau cov neeg mob ntsuam xyuas.
Cov txheej txheem sedation:
Sedation rau cov txheej txheem luv luv nrog rau endoscopy, kev cuam tshuam, thiab hluav taws xob, muab kev ntxhov siab, kev ua xua, thiab rov qab sai, txhim kho kev ua raws thiab kev nplij siab.
Preoperative / postoperative tswj:
Preoperative ntxhov siab vim nyem, postoperative shivering tiv thaiv thiab adjuvant analgesia, txhim kho zoo rov qab zoo thiab cov neeg mob kev.
R & D thiab sau npe:
Siv rau kev tsim kho, kev tshawb fawb txog kev ruaj ntseg, kev ntsuam xyuas qhov sib xws, kev sim tshuaj pharmacodynamic thiab toxicological, nrog rau cov qauv siv thiab kev xeem npaj rau kev sau npe.
Ntim thiab thauj
Xav txog qhov rhiab heev ntawm Dexmedetomidine HCl Txhaj rau lub teeb thiab qhov kub thiab txias, tag nrho - txheej txheem kev tiv thaiv txheej txheem raug kho kom ruaj khov zoo los ntawm lub Hoobkas mus rau kev xa khoom.
Lub teeb- pov thawj ntim ntim:
Xim av ampoules los yog lub teeb- tiv thaiv vials rau cov ntim tsis muaj menyuam, ntxiv rau lub teeb- cov thawv pov thawj thiab cov khoom ntim tsis zoo los tiv thaiv lub teeb -induced degradation thiab xyuas kom tsis muaj menyuam thiab meej.
Kev tswj kub thiab av noo:
Txias- cov tsheb thauj mus los thoob plaws nrog qhov ntsuas kub tsawg dua lossis sib npaug li 20 degree, nruab nrog -lub sijhawm ntsuas kub thiab av noo tiag tiag kom tsis txhob muaj qhov kub thiab txias -thaw cycles thiab tswj kev ruaj khov.
Warehouse Management:
GMP- ua raws li cov chaw khaws khoom txias nrog cais cia thiab FIFO txoj cai; Cov qauv kev ruaj ntseg tsis tu ncua thiab txee- ceeb toom lub neej thaum ntxov los txhawb R&D, tus tsav, thiab cov khoom lag luam.
Kev thauj mus los raws cai:
Tsim nyog GSP-cov chaw muab tshuaj logistics tau ntawv pov thawj nrog kev poob siab tag nrho, poob qis, thiab tiv thaiv kev kis kab mob. Ua kom tiav kev lis kev cai thiab cov ntaub ntawv rau kev xa khoom thoob ntiaj teb kom ntseeg tau tias kev xa khoom raws li thoob ntiaj teb.
Tag nrho -chain traceability:
Tag nrho traceability los ntawm ntau lawm, warehousing, tsheb thauj mus los rau tus me nyuam, nrog ceev ceev teb rau txawv txav los xyuas kom meej cov khoom muaj kev ruaj ntseg thiab cov neeg siv khoom txoj cai.
Peb Qhov Zoo
Mature sterile txheej txheem, ruaj khov zoo Txais kev siv pov thawj kev txhaj tshuaj tshuab los xyuas kom tsis muaj menyuam, pyrogen -dawb, thiab pom -particle- dawb zoo nrog cov khoom zoo sib xws. Kev ua raws li GMP tag nrho ua tau raws li cov cai ntawm ChP, USP, thiab EP rau kev siv tshuaj kho mob thiab kev sau npe.
Precise impurity tswj, muaj kev nyab xeeb thiab txhim khu kev qha Kev tswj hwm nruj ntawm cov khoom muaj feem xyuam, isomers, residual solvents, thiab endotoxins, nrog rau qhov tseeb thiab kev nyab xeeb siab. Txhua batch muab tag nrho COA, HPLC chromatograms, sterility thiab pyrogen cov ntaub ntawv los txhawb cov ntawv sau npe.
Loj -scale khoom ruaj khov, txhim khu kev qha xa khoom nruab nrog loj - nplai kab ntau lawm nrog cov khoom muag txaus thiab kev xa khoom ruaj khov. Cov lus teb ceev ceev rau me me - nplai, tsav, thiab kev txiav txim ua lag luam ua kom cov khoom siv txuas ntxiv thiab txo cov kev pheej hmoo ntawm cov saw hlau.
Ua kom tiav cov ntaub ntawv ua raws cai, kev txhawb nqa kev qhia tag nrho ntawm GMP cov ntaub ntawv ua raws cai, COA, MSDS, cov ntaub ntawv txheej txheem, thiab cov ntaub ntawv ruaj ntseg muaj. Pab neeg tshaj lij txhawb kev tsim kho kom zoo, kev ntsuas qhov sib xws, thiab kev sau npe sau npe nrog kev txhawb nqa tag nrho.
Kev ntim khoom thiab kev khaws cia, kev ruaj ntseg zoo Customized light-proof, sterile, shockproof ntim thiab txias cia thiab tsheb thauj mus los daws teeb meem kom tag nrho - txheej txheem sterility, stability, thiab kev nyab xeeb, guaranteeing cov khoom raws li kev soj ntsuam thiab R&D qauv thaum xa khoom.
FAQ
Yog tias koj paub txog cov kev xav tau sedative hauv perioperative thiab ICU chaw thiab txaus siab rau cov khoom siv ruaj khov thiab cov kev pabcuam kev txhawb nqa ntawm siab -Dexmedetomidine HCl Txhaj Tshuaj zoo, txais tos hu rau peb rau kev koom tes. Peb muab cov lus hais raug thiab raws sij hawm, ib qho - rau- ib qho kev txhawb nqa, thiab cov phiaj xwm kev koom tes tsim kho los ntawm R&D kev sim thiab kev kuaj xyuas rau kev lag luam, muab kev txhawb nqa ruaj khov thiab txhim khu kev qha rau koj cov tshuaj loog thiab cov chaw kho mob tseem ceeb.
Cim npe nrov: Dexmedetomidine hydrochloride txhaj tshuaj, Tuam Tshoj dexmedetomidine hydrochloride txhaj tshuaj manufacturers, lwm tus neeg, Hoobkas
