HK Neopharm Limited yog ib qho ntawm feem txhim khu kev qha manufacturers thiab lwm tus neeg ntawm octreotide api nyob rau hauv Suav teb, featured los ntawm cov khoom zoo thiab tus nqi zoo. Thov so assured mus yuav octreotide api hauv Tshuag ntawm no thiab tau txais cov lus hais los ntawm peb lub hoobkas. Customized xaj yog txais tos.
Octreotide API (CAS 83150-76-9) yog ib qho hluavtaws ua haujlwm ntev somatostatin analog, uas yog ib qho tseem ceeb polypeptide cov tshuaj muaj tshuaj tiv thaiv qog thiab qog cov tsos mob. Nrog cov qauv tshuaj lom neeg ruaj khov thiab cov khoom siv sib txuam sib luag, nws ua haujlwm raws li cov khoom siv tseem ceeb rau cov tshuaj kho mob neuroendocrine hlav, qog nqaij hlav hauv plab thiab lwm yam kab mob. Raws li nws cov cim tshuaj tshwj xeeb, CAS 83150-76-9 ua kom lub cim tshwj xeeb thiab kev taug qab ntawm Octreotide API hauv ntiaj teb R & D, ntau lawm, sau npe thiab ncig.
Technical Specifications
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Khoom npe |
Octreotide API |
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Synonyms |
CAS 83150-76-9, Octreotide hmoov |
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Yam ntxwv |
Dawb kom tawm -dawb amorphous lossis lyophilized hmoov |
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CAS Nr |
83150-76-9 |
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Assay |
Ntau dua los yog sib npaug rau 99.0% (HPLC, Raws li COA) |
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Formula |
C49H66N10O10S2 |
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Pob |
Pob txheej txheem |
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Cia |
Khaws ntawm -20 degree |
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Qauv |
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Peb koom tes nrog GMP, FDA thiab CEP certified khub factories, thiab muab cov tuam txhab tshuaj thoob ntiaj teb nrog Octreotide hmoov uas ua raws li USP, EP thiab CP thoob ntiaj teb cov tshuaj pharmacopoeia cov qauv. Peb txhawb R&D thiab kev lag luam ntawm kev tiv thaiv -cov tshuaj qog noj ntshav nrog cov saw hlau ruaj khov, kev tswj xyuas nruj thiab ua tiav cov ntaub ntawv sau npe. Peb tswj hwm cov nqi Octreotide pob tshab thiab tsim nyog thiab tus nqi Octreotide, thiab muab cov neeg siv khoom nrog tus nqi - cov khoom siv raw zoo.
Cov yam ntxwv ntawm cov khoom
Octreotide API (CAS 83150-76-9) yog tsim los ntawm cov khoom siv-theem synthesis, ntau theem npaj chromatographic purification thiab sterile lyophilization refining. Kev tsim khoom, sub-packaging thiab sealing yog ua tiav nyob rau hauv chav kawm B / A huv si los tswj kev pheej hmoo impurities xws li peptide fragments, deamidation khoom, oxidation khoom, residual solvents, hnyav hlau thiab kab mob ntawm qhov chaw. Nyob rau hauv cov nqe lus ntawm kev tswj kom zoo, qhov kev ntsuam xyuas yog ntau tshaj los yog sib npaug rau 99.0%, siab tshaj ib impurity Tsawg tshaj los yog sib npaug rau 0.15%, tag nrho impurities Tsawg dua los yog sib npaug rau 0.5%, cov kab mob endotoxins<0.5 EU/mg, moisture ≤3.0%. These key indicators exceed to international pharmacopoeia requirements and can meet the production needs of high-safety anti-tumor preparations such as injections and sustained-release microspheres.
Octreotide hmoov yog dawb los yog tawm -dawb xoob lyophilized hmoov, tsis muaj ntxhiab thiab tsis yog -caking, nrog dej solubility zoo heev. Nws dissolves sai sai hauv dej rau kev txhaj tshuaj thiab tsis siv lub tshuab nrog cov ntshiab re-solution yam tsis muaj txawv teb chaws, yooj yim rau formulation npaj thiab sterile filtration. Cov khoom lag luam muaj cov qauv siv lead ua zoo sib xws, cov khoom sib txawv me me ntawm cov khoom faib tawm thiab cov fluidity ruaj khov. Nws yog sib xws nrog cov txheej txheem nyuaj xws li microsphere embedding, sustained - tso tshuaj loading thiab lyophilization molding. Nws muaj kev ruaj ntseg zoo uas tsis muaj qhov poob qis hauv purity thiab potency nyob rau hauv lub txee lub neej.
Octreotide API tuaj yeem khi rau somatostatin receptors (SSTR2/5) nrog kev xaiv siab. Nws cov haujlwm inhibitory yog qhov siab dua li ntawm ntuj somatostatin. Ib nrab- lub neej txuas ntxiv mus rau 1.5-2 teev, thiab qhov ntev ntawm - kev npaj ua yeeb yam tuaj yeem ncav cuag 4-6 lub lis piam.
Full -Cycle Quality Control & Consistent Quality
Tag Nrho -Txoj kev Traceability Management
Peb koom tes nrog cov koom tes thoob ntiaj teb cov koom haum koom tes los siv tag nrho -chain traceability tswj rau Octreotide API, suav nrog cov khoom pib, peptide synthesis, cleavage thiab purification, lyophilization, sterile sieving, sub- ntim, ntim thiab tshuaj xyuas cov khoom tiav. Txhua batch ntawm cov khoom yog muab ib tug tshwj xeeb batch naj npawb, thiab cov txheej txheem ntau lawm yog kaw nyob rau hauv lub sij hawm ntawm lub sij hawm kom ua tiav tag nrho traceability, xyuas thiab retesting.
Strict Standard thiab Compliance Assurance
Octreotide API (CAS 83150-76-9) yog ua raws li ICH Q7, GMP, USP, EP thiab CP cov qauv. Ib qho kev sim tshwj xeeb rau kev tiv thaiv qog nqaij hlav polypeptides yog siv, suav nrog kev sim tag nrho xws li kev pom zoo ntawm cov qauv, kev soj ntsuam, cov tshuaj muaj feem xyuam, cov kuab tshuaj seem, cov khoom tsis huv, cov kab mob microbial txwv, cov kab mob endotoxin, clarity thiab pH nqi. Cov kev ntsuas tau zoo tau ua tiav nrog thoob ntiaj teb cov tshuaj pharmacopoeias, txhawb kev sau npe tshuaj hauv kev lag luam thoob ntiaj teb suav nrog Tuam Tshoj, Tebchaws Meskas, Tebchaws Europe thiab Nyiv. Peb muab kev ua raws cai thiab ruaj khov Octreotide API muab rau cov tuam txhab tshuaj thiab txo qis kev tso npe thiab kev pheej hmoo ntau lawm.
Nruam Qhov System Optimization
Kev txhawb nqa los ntawm kev txhim kho thev naus laus zis txuas ntxiv ntawm cov koom haum koom tes, peb niaj hnub ua kom zoo dua qub thiab ua kom huv ntawm cov txheej txheem Octreotide API los txhim kho cov khoom purity thiab tawm los thaum txo qis impurity theem thiab Octreotide tus nqi. Peb tau tsim ib qho kev ua tiav rau kev sib txawv, kev hloov pauv, kev tshuaj xyuas kev ruaj ntseg thiab kev tshuaj xyuas txhua xyoo. Kev txheeb xyuas cov txheej txheem thiab kev ntsuas thoob ntiaj teb tau ua tsis tu ncua los xyuas kom meej thiab ruaj khov zoo ntawm txhua pawg, muab cov neeg siv khoom nrog ntev - lub sij hawm thiab txhim khu kev qha raw khoom.
Daim ntawv thov Scenario
Octreotide API tsuas yog siv los ua cov khoom siv tshuaj nquag thiab yuav tsum tau tsim rau hauv cov khoom siv tshuaj los ntawm cov txheej txheem tsim ua ntej siv tshuaj kho mob. Cov txheej txheem tseem ceeb ntawm daim ntawv thov yog raws li hauv qab no.
Neuroendocrine Tumor Therapeutic Tshuaj
Kev npaj ua los ntawm Octreotide muaj qhov tso tawm ntau dua lossis sib npaug li 80% rau cov qog nqaij hlav neuroendocrine- cov tsos mob (xws li, raws plab, mob plab) thiab cov qog loj hlob ntawm ntau dua lossis sib npaug li 65%. Lawv tuaj yeem txo qhov kev cuam tshuam thiab metastasis ntawm cov qog nqaij hlav gastroenteropancreatic thiab tau txais txiaj ntsig zoo los ntawm cov neeg mob siab heev. Nrog rau cov kab mob tsis tshua muaj tshwm sim, cov kev tsis zoo tshwm sim feem ntau yog mob me me mus rau nruab nrab cov kab mob plab hnyuv nrog rau qhov tshwm sim.<8%. It has reliable long-term safety and provides stable clinical benefits for tumor patients.
Cov qog nqaij hlav-Cov tshuaj tiv thaiv thaum muaj xwm ceev thiab cov tsos mob ntsig txog
Kev npaj ua los ntawm Octreotide API tuaj yeem siv los tswj cov xwm txheej tseem ceeb xws li mob raws plab, ntuav, plab hnyuv los ntshav, pancreatic fistula thiab plab hnyuv fistula tshwm sim los ntawm cov qog nqaij hlav, tshwj xeeb tshaj yog rau kev kho mob ntawm cov neeg mob qog nqaij hlav. Lawv tuaj yeem txo cov tsos mob sai sai, txo cov kev pheej hmoo cuam tshuam thiab tsim cov xwm txheej rau kev kho mob.
Adjuvant Therapeutic Drugs rau Gastroenteropancreatic hlav
Cov tshuaj npaj nrog Octreotide hmoov raws li cov khoom siv tseem ceeb tuaj yeem siv rau kev kho mob ntawm cov qog nqaij hlav xws li mob qog noj ntshav, mob qog noj ntshav thiab mob qog noj ntshav. Los ntawm inhibiting angiogenesis thiab cov tshuaj hormone- tsav txoj hauv kev, lawv tuaj yeem txo qhov kev pheej hmoo rov qab ua dua tshiab, txhim kho chemoradiotherapy rhiab heev thiab txhim kho tag nrho cov txiaj ntsig kho.
R&D ntawm Anti-Tumor Innovative Preparations
Nrog kev xaiv cov neeg txais siab thiab muaj kev nyab xeeb zoo, Octreotide API tuaj yeem siv rau hauv R&D ntawm cov tshuaj tshiab xws li ntev - ua kom ruaj khov - tso tawm kev npaj, npaj npaj, cov khoom siv hluav taws xob sib txuas thiab cov tshuaj tiv thaiv kab mob - qog nqaij hlav. Nws muaj peev xwm nthuav dav hauv thaj chaw ntawm kev kho kom raug thiab radionuclide kev kuaj mob thiab kev kho mob, muab siab -cov khoom siv raw zoo rau kev txhim kho cov tshuaj tiv thaiv- qog cov tshuaj tshiab.
Ntim thiab thauj
Octreotide API yog lub tshuab nqus tsev- kaw hauv cov tshuaj- qib qis- adsorption tshwj xeeb peptide fwj / aluminium foil hnab nrog ua- hauv cov khoom siv desiccant thiab lub teeb- cov ntaub ntawv pov thawj. Nws yog nruab nrog thermal rwb thaiv tsev thiab poob siab- cov ntaub ntawv pov thawj sab nrauv, uas muaj cov khoom ntawm lub teeb tiv thaiv, tiv thaiv ya raws, oxidation tsis kam, degradation kuj thiab muaj kuab paug tsis kam ua kom muaj kev ruaj ntseg ntawm peptide raw khoom. Customized ntim cov kev pabcuam kuj tau txais kev txhawb nqa.
Logistics nruj me ntsis siv cov tshuaj logistics thiab txias - saw tsheb thauj mus los cov qauv nrog puv - txheej txheem 2-8℃qis kub thiab tiv thaiv lub teeb. Kev thauj mus los thoob ntiaj teb ua raws li UN cov kev cai thiab txias- cov kev xav tau ntawm cov saw hlau, muab kev thauj khoom huab cua thiab kev nthuav qhia thoob ntiaj teb nrog tag nrho - txheej txheem ntsuas kub thiab taug qab txoj hauv kev kom nyab xeeb thiab nyob rau - lub sijhawm xa khoom. Peb muaj tag nrho cov kev tsim nyog export, kev lis kev cai clearance cov ntaub ntawv thiab freight forwarding kev pab cuam los xyuas kom meej zoo thiab raws li thoob ntiaj teb logistics kev pab cuam.
Peb Qhov Zoo
Tus nqi tsim nyog thiab khoom siv thoob ntiaj teb
Octreotide tus nqi yog xam pob tshab raws li cov lus qhia tshwj xeeb thiab yuav ntim nrog cov nqi sib tw. Kev txiav txim ntau Octreotide tsim nyog rau tus nqi nyiam uas tuaj yeem ua tau raws li kev xav tau ntawm kev lag luam loj. Muaj peev xwm tsim tau ruaj khov ua kom muaj kev ruaj khov rau cov neeg siv khoom thoob ntiaj teb. Rau cov lus hais tshwj xeeb, thov nrog cov neeg sawv cev ua lag luam.
R&D Kev Pabcuam thiab Kev Pabcuam Customized
Peb tuaj yeem muab cov qauv dawb Octreotide rau cov neeg siv khoom R & D muaj peev xwm, uas tsim nyog rau kev tshuaj xyuas tshuaj, kev sim txoj kev txhim kho, kev sim tshuaj ua ntej thiab lwm yam R & D thaum ntxov. Cov qauv purity thiab zoo yog zoo ib yam nrog cov khoom loj. Peb kuj muab kev pabcuam kev pabcuam customized kom tau raws li qhov xav tau ntawm kev npaj sib txawv.
FAQ
Cim npe nrov: Tuam Tshoj octreotide API manufacturers, lwm tus neeg, Hoobkas
